![]() Thinning of the arms and legs and muscle weakness, Unexplained weight gain, particularly around the neck and midsection, ![]() ![]() The most common symptoms of Cushing’s disease are: Most ACTH-secreting tumors are benign (not cancer), though in rare cases, they can become cancerous. Women in their 30s and 40s are most commonly diagnosed with the condition, although men and women of all ages can be affected. The exact cause of ACTH-secreting tumors is unknown. When the body produces too much cortisol, it leads to a range of symptoms. Learn moreĬortisol affects metabolism and under normal circumstances helps the body recover from stress caused by surgery, an injury, or an infection. Learn how Terri found the right care plan for Cushing's disease at Memorial Sloan Kettering after years of misdiagnoses.
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